The drug "Longidase" (candles). Reviews. Instructions
The drug "Longidase" (candles) is intended forrectal or intravaginal administration. The agent has proteolytic activity of prolonged (prolonged) action. The medication has an immunomodulatory, antioxidant, chelating and anti-inflammatory (moderately expressed) effect. When administered rectally, absorption into the systemic circulation occurs rather quickly. The drug reaches its maximum concentration after an hour. Bioavailability funds - about 70%. The medicine "Longidase" (candles, experts' reviews confirm this) is characterized by a high rate of distribution of organs and tissues. The medicine passes the BBB. Excretion is carried out mostly by the kidneys.
Application
Candles of "Longidase" are used in urologicalpractice. Indications include prostatitis of chronic course, interstitial cystitis, Peyronie's disease, ureter stricture and urethra. The drug is recommended for the prevention of scarring and the formation of strictures after surgery on the bladder, urethra, ureter. The drug "Longidase" (suppositories) (feedback from specialists confirm this) helps to reduce the manifestations of benign prostatic hyperplasia at the initial stage. In surgery, medication is indicated with long-term healing wounds, for the treatment and prevention of adhesions after operations on the peritoneum. Candlesticks "Longidase" in gynecology are used for tubal peritoneal infertility, intrauterine synechia, chronic endomyometritis.
Contraindications
Not recommended for pregnancy,hypersensitivity. No drug is prescribed before the age of twelve, in the presence of malignant tumors, hypersensitivity. Caution during therapy or prevention should be observed in patients with renal insufficiency, with anamnestic data on pulmonary bleeding.
Method of dosing 
The drug "Longidase" (candles) - reviews of doctorsindicate this - rectally recommended to use after bowel movement. Usually, it is prescribed by suppository at night (intravaginally or rectum). One course involves ten to twenty introductions. Depending on the tolerability, severity of the disease, the age of the patient, the treatment regimen can be adjusted. So, the drug can be used every other day or with a break of two to three days.
Adverse reactions when using the drug "Longidase" (candles)
Patients' testimonies indicatesatisfactory tolerability of the medicament. In some cases, the development of allergic reactions is likely. As a rule, they are caused by the presence of hypersensitivity to the components. If these side effects occur, consult a doctor.
