"Kutiveyt" (ointment) - instructions for use. Description of the preparation

What are the uses of the drug "Kutiveyt"(ointment)? Instructions for use of the drug, its analogues, indications, forms of release and composition will be described in this article. From it you will learn about how much this tool costs, what contraindications it has, whether there are side effects, etc.

Composition, release form, description and packaging

What are the components of the drug?“Kutivate” (ointment)? Instructions for use states that the active substance of this form of the drug is fluticasone propionate. It also includes sorbitan sesquioleate, liquid paraffin and microcrystalline wax.

Translucent and homogeneous ointment intendedfor outdoor use only. It has a white or almost white color. The drug is sold in aluminum tubes (15 g), which are in cardboard packaging.

What other form of medicine is used for the drug, Cutivate?

Cream for external use (0.05%) hashomogeneous and soft texture, as well as white or almost white color. Fluticasone propionate is also an active component of this form. In addition, the drug includes such excipients as sodium phosphate, liquid paraffin, cetostearyl alcohol, isopropyl myristate, propylene glycol, ketomacrogol, imidourea, citric acid monohydrate and purified water.

The drug goes on sale in aluminum tubes (15 g), placed in cardboard boxes.

In addition to the two listed forms of medication,pharmacies can also find other types of funds “Kutivayt” - nasal spray and spray for inhalation. The active ingredients of the mentioned preparations are the same components as the cream ointment. However, their purpose is somewhat different.

Pharmacological characteristics

What is the drug "Kutiveyt"? Hormonal or not this drug? According to experts, this drug is a glucocorticosteroid agent with a pronounced anti-inflammatory effect.

As stated above, all forms considereddrugs contain such an active ingredient as fluticasone propionate. This is a glucocorticosteroid substance. When applied topically, it eliminates burning, redness and itching, and also significantly reduces the intensity of the existing inflammation.

When used externally, the drug haspronounced anti-edema and antiallergic action. At the same time, there is no negative effect of the above mentioned means on the cardiovascular, respiratory and nervous systems.

Pharmacokinetics

Is Kutiveit medication absorbed (ointment)? Instructions for use states that when used externally, the fluticasone propionate bioavailability is rather low. This is due to its limited absorption through the skin, as well as intensive metabolism during the passage through the liver.

The drug, which entered the systemic circulation after application to the skin, quickly inactivated. In this regard, its systemic impact is minimal.

The main route of metabolism of the drug ishydrolysis to carboxylic acid. The formed metabolite has a rather weak glucocorticoid activity. The active ingredient of the drug is not bound to melanin and does not accumulate in the tissues.

Fluticasone propionate is rapidly eliminated, and also has a very high metabolic clearance.

Indications for use of cream and ointment

In which cases the hormonal drug “Kutivate” (ointment) is prescribed? Instructions for use inform patients that the drug is used to treat skin diseases.

Thus, the following indications are indications for use of the mentioned forms of the drug:

• atopic dermatitis;
• eczema;
• seborrheic dermatitis;
• psoriasis;
• Erythroderma (in addition to systemic therapy);
• contact dermatitis;
• flat red lichen;
• neurodermatosis, including herpes simplex;
• lupus erythematosus discoid;
• insect bites.

Allergic dermatosis can be treated with cream in children older than one year. As for the ointment, then this form of the drug can be prescribed for babies already from 6 months.

Indications for use of nasal spray and aerosols

In which cases the patient may be assignedspray "kutivate"? Reviews of experts say that the nasal remedy perfectly treats allergic rhinitis. As for the aerosol, it is actively used for the prevention of exacerbations of asthma.

Contraindications to the use of all forms of the drug

If there are any deviations, it is forbidden to use the drug "Kutivate" (cream, ointment, spray, spray)? According to the instructions, all forms of funds can not be used for:

• pink acne;
• common eels;
• at children's age till one year for cream, till 6 months for ointment and till 4 years for spray;
• perioral dermatitis;
• viral and fungal infections of the skin;
• perianal and genital pruritus;
• hypersensitivity to substances substances.

It should also be noted that the funds in question should be prescribed with extreme caution during pregnancy and during lactation.

Ways to use ointment and cream

How to use external drug"Kutivate"? The use of ointment and cream should be administered only on prescription. In the treatment of chronic and acute dermatosis, the drug is applied to the affected area with a thin layer twice a day. The duration of use of the hormonal drug is two weeks.

To reduce the recurrence of a disease such asallergic dermatosis, after reaching a therapeutic effect, the frequency of applying ointment and cream is reduced. In this case, the drug should be used once twice a week. In this case, occlusive dressings should be excluded.

It should also be noted that the ointment and cream should be applied to all previously affected skin, as well as to those where the disease may occur.

Methods of use and dosage of spray and aerosol

How to use the local drug"Kutivate" (the price of the funds is presented a little further)? For adults, a nasal spray is recommended for use in the morning with 100 mcg in each nostril, and for children under 12 years old - 50 mcg.

As for the aerosol for inhalation, thenFor bronchial asthma of medium, mild and severe degree, the drug in this form is prescribed twice a day, 250–500 µg, 100–250 µg and 500 µg, respectively. Teenagers under 16 years old need to use the drug at 50-100 mg.

Overdose

The likelihood of acute overdose consideredmeans extremely low. But with the wrong use or chronic overdose, the patient may develop signs of hypercorticism. In this case, the use of the medication should be immediately stopped. However, the drug should be discontinued gradually, under the supervision of the attending physician (to avoid the risk of oppression of the work of the adrenal cortex).

Side effects after using ointment and cream

Does the drug have side effects? Reviews of specialists inform that in some cases, this drug really contributes to the appearance of undesirable reactions. Among them are the following:

• Local reactions: atrophic skin changes (hypertrichosis, thinning, dilation of blood vessels, hypopigmentation and stria), itching, burning, exacerbation of signs of dermatosis, development of contact and allergic dermatitis, as well as secondary infections (with occlusive dressings).
• Systemic reactions: symptomatic hypercortisolism (with long-term use of the drug in high dosages, as well as when applying an external agent to large areas of skin). Most often, this side effect is observed in young children and young children, as well as when using occlusive dressings. Very rarely, the use of ointments and creams can trigger the development of pustular forms of psoriasis.

Side effects after using spray and aerosols

Nasal spray often causes irritation.nasopharynx, perforation of the nasal septum, as well as the feeling of unpleasant taste and smell. As for the inhalation aerosol, this form of the drug contributes to the appearance of oral mucous candidiasis, hoarseness and paradoxical bronchospasm.

special instructions

Long-term use of ointments and creams in high dosages, especially if the drug was applied to large areas of the skin (especially in children), can cause the suppression of the function of the adrenal cortex.

High absorption of the external drug in childrenobserved more often than in adults. Therefore, they are more susceptible to systemic effects of the drug. In this regard, this tool should be used in small doses, which provide a therapeutic effect.

With long outdoor use atrophicchanges most often appear on the face. This fact should be considered during the treatment of such deviations as discoid lupus erythematosus, psoriasis and severe eczema.

When applying ointment and cream on the eyelids, you must avoid getting the medication in the eyes, as this may cause glaucoma or local irritation.

With extreme caution, an inhalation aerosol is prescribed for pulmonary tuberculosis. In this case, treatment should not be abruptly canceled.

Nasal spray should be used at regular intervals.

The drug "Kutivate": analogues and prices

Analogues of the considered agents are the following drugs: "Nazarel", "Fluticasone propionate", "Fliksonaze", "Fluticasone" and "Fliksotid".

How much does the "Kutivate" cost? The price of different forms of the drug can vary considerably. For example, ointment can be purchased for 290 Russian rubles, and cream - for 330.

About the same prices have nasal spray and spray for inhalation.

Reviews about the tool

The drug "Kutivate" is a hormonal agent. This fact is very frightening to the patients to whom he was appointed. However, after the first use, they note its high efficiency.

According to the patient reviews, the ointment and cream quickly treat all types of allergic dermatosis. Also do well with the task and spray with an aerosol.

However, it should be noted that there is suchA category of people who complain of a large number of side effects. In this case, patients are recommended to cancel the use of the drug and use a safer analogue.