Loperamide-Acry - quality care for diarrhea
Loperamide-Acry is a drug that is widely used in the treatment of diarrhea. This drug helps to reduce the motility of the gastrointestinal tract.
Loperamide is a description of the drug
This medicine is available in the form of capsules ortablets, each containing 2 mg of loperamide hydrochloride. Also in the composition of this drug as ancillary substances include cornstarch, talc and lactose.
Loperamide-Acry is attributed to the presence ofpatient acute form of non-infectious diarrhea, as well as mild to moderate degree of infectious diarrhea. The drug begins to exert its effect very quickly and lasts for 4-6 hours. The use of loperamide-acry allows to reduce the motility of the gastrointestinal tract, increase the tone of the anal sphincter, thus reducing the urge to defecate and retaining feces in the rectum.
Thanks to Loperamide, suction timeelectrolytes and water increases and thereby their loss is significantly reduced. There is a decrease in hypersecretion of mucus in the colon, an antisecretory effect. Due to the inhibition of calmodulin and calcium channel blockade, as well as suppression of intestinal peptides and neurotransmitters, which increase the permeability of plasma membranes, Loperamide has a positive effect on intestinal secretion.
Loperamide - from what does it help?
As already mentioned above, this drugis one of the most effective medicines in the fight against diarrhea. Despite the fact that it is a synthetic opiate, the drug does not have a systemic narcotic effect and does not penetrate it through the blood-brain barrier. Loperamide-Acry well helps with motor and functional diarrhea, but it is ineffective if the patient has diabetic enteropathy, amyloidosis or scleroderma. Very often in these diseases, the use of this drug may even increase diarrhea.
Dosage Loperamide Acry
For the treatment of adults at the initial intake it is recommended to use 4 mg of the drug, and with subsequent application of 2 mg, after the act of defecation with a liquid stool.
If the patient has chronic diarrhea, then also withInitially, 4 mg, then one to six times a day, 2 mg of loperamide. But remember that the daily dose of this drug should not exceed 16 mg.
It is permitted to use this agent forchildren who are more than 5 years old, but they are given 2 mg of the drug after each defecation with a liquid stool. If a child has chronic diarrhea, then the drug is used 1 to 5 times a day.
Possible side effects
If long-term use of this drug is carried out, there may be constipation, drowsiness, nausea, very rarely there may be intestinal obstruction, as well as a toxic megacolon.
It is contraindicated to apply the drug in the following cases:
- presence of intestinal obstruction in the patient;
- if the patient has acute ulcerative colitis or pseudomembranous colitis;
- Do not prescribe a drug for pregnant women who are in the first trimester;
- Also, the drug is not prescribed for children under the age of 2 years and those people who have hypersensitivity to the components of this remedy.
Loperamide-Acry very carefully must be used forchildren aged 2 to 5 years, as well as in the presence of dehydration, infectious diarrhea. It is not recommended to administer the drug to people who have liver dysfunction, as well as to older people, since they are at risk of losing fluid and salts. If the drug has not had a positive effect for 2 days, it should be discarded. If there was a need to receive Loperamide-Acrya by a woman during lactation, then from breastfeeding for the period of taking this remedy should be abandoned.
When signs of an overdose of the drug as an antidote are used Naloxone.