The medicine "Acetylcysteine". Instructions for use
Agent "Acetylcysteine" instructions for usecharacterizes as mucolytic medicine. The drug helps to increase the volume and liquefaction of phlegm, facilitating its excretion from the bronchi. The activity of the preparation is related to the properties of sulfhydryl groups. They are able to rupture disulfide bonds in acid mucopolysaccharides of sputum. This provokes depolarization of mucoproteins and a decrease in the viscosity of mucus. The drug "Acetylcysteine" (instructions for use contains such information) has an antioxidant property due to the presence of SH-group, which interacts and neutralizes oxidative electrophilic toxins. The agent helps to enhance the synthesis of glutathione, an important antioxidant element in intracellular protection, which ensures the maintenance of functioning and morphological cellular integrity. After penetration into the bloodstream, the drug binds to plasma proteins by 50%. The drug passes through the placental barrier, is present in the amniotic fluid. A small amount of medication goes through the intestines.
Purpose of the drug "Acetylcysteine"
Drugs with mucolytic effects are prescribedat pathologies of respiratory organs and conditions complicated by production of viscous, mucopurulent, difficultly separated sputum. Recommended therapy for bronchitis of chronic and acute type, tracheitis, due to viral or bacterial infection, bronchiectasis, pneumonia. To the indications for the use of the drug "Acetylcysteine" the instruction for use includes atelectasis (as a result of corking in the bronchi), bronchial asthma. As part of the complex effect, the drug is recommended for cystic fibrosis. The medicine is shown after injuries and operations to remove mucus from the bronchi, as well as to improve sputum secretion with sinusitis.
The medicine "Acetylcysteine" is intended for inhalations. Dosage - 2-5 ml of a 20% solution three to four times a day. The duration of the procedure is 15-20 minutes.
The drug "Acetylcysteine". Instructions for use. Adverse Reactions
Usually the tolerance of the drug is satisfactory. Rarely there is a nausea (caused, as a rule, by a specific smell of medicament), local irritation in the respiratory tract, reflex cough. Some patients may have rhinitis, stomatitis.
The medicine "Acetylcysteine". Instructions for use. Contraindications
Do not prescribe medication for exacerbations of ulcersduodenal ulcers or stomach, pulmonary hemorrhage, hemoptysis, hypersensitivity, bronchial asthma without thickening of sputum. The expediency of conducting therapy during the prenatal period and during lactation is determined by a specialist.
When working with a medicine it is recommended to use glass vessels, to avoid contact of the agent with rubber or metals in order to avoid the formation of sulfides with a specific odor.